REFERENCE / 02PREPARATION COMPATIBILITY
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mixability matrix
A quick-reference table for deciding whether selected compounds belong in a shared draw or should remain in separate vials.
15listed as compatible
7single-vial entries
pHprimary comparison variable
| # | Peptide | Target / reconstituted pH | Vial status | Mixing rationale & notes |
|---|---|---|---|---|
| — | NAD+ | 2.0 – 3.5Highly acidic | 🛑MUST BE SINGLE | Extreme acidity rapidly denatures and degrades delicate peptide chains if mixed. |
| 01 | MOTS-c | 6.5 – 7.5Near neutral | 🟢CAN BE MIXED | Requires near-neutral pH to prevent unfolding. Safe to mix with 5-Amino-1MQ or SS-31. |
| 02 | 5-Amino-1MQ | 5.5 – 7.0Mildly acidic / neutral | 🟢CAN BE MIXED | Small-molecule salt structure that tolerates neutral peptide buffers well. |
| 03 | BPC-157 | 6.0 – 7.0Near neutral | 🟢CAN BE MIXED | Highly stable; commonly combined with TB-500 ("Wolverine Stack") or GH secretagogues. |
| 04 | TB-500 | 6.0 – 7.0Near neutral | 🟢CAN BE MIXED | Stable sequence; pairs well with near-neutral repair peptides in the same draw. |
| 05 | Ipamorelin | 6.0 – 7.0Near neutral | 🟢CAN BE MIXED | Standard GH secretagogue; routinely paired with CJC-1295 (no DAC) immediately before injection. |
| 06 | CJC-1295 (no DAC) | 6.0 – 7.0Near neutral | 🟢CAN BE MIXED | Synergistic GHRH analog; chemically compatible with Ipamorelin in neutral pH. |
| 07 | SS-31 (Elamipretide) | 5.5 – 7.0Near neutral | 🟢CAN BE MIXED | Mitochondrial peptide; shares a compatible neutral pH window with MOTS-c and 5-Amino-1MQ. |
| 08 | Thymosin Alpha-1 | 6.5 – 7.5Near neutral | 🟢CAN BE MIXED | Stable immune-modulating peptide at near-neutral pH. |
| 09 | GHK-Cu | 5.5 – 6.5Slightly acidic | 🟢CAN BE MIXED | Copper tripeptide; mixes with neutral healing peptides, though it can cause a slight sting standalone. |
| 10 | Epithalon | 6.0 – 7.0Near neutral | 🟢CAN BE MIXED | Small, durable tetrapeptide; stable alongside standard neutral protocols. |
| 11 | DSIP | 6.0 – 7.0Near neutral | 🟢CAN BE MIXED | Stable short peptide; usually kept single because of bedtime dosing timing. |
| 12 | Melanotan II | 5.5 – 6.5Slightly acidic | 🟢CAN BE MIXED | Thermally and chemically stable; safe to pair with neutral compounds. |
| 13 | PT-141 | 5.0 – 6.5Mildly acidic | 🟢CAN BE MIXED | Stable cyclic peptide; typically administered alone because of as-needed (PRN) usage. |
| 14 | Sermorelin | 5.0 – 6.5Mildly acidic | 🟢CAN BE MIXED | Fragile GHRH fragment; can pair with Ipamorelin if drawn and administered immediately. |
| 15 | Kisspeptin-10 | 6.0 – 7.0Near neutral | 🟢CAN BE MIXED | Rapid-acting signaling peptide; stable in neutral bacteriostatic water. |
| 16 | IGF-1 LR3 | 3.0 – 4.0Acidic buffer | 🛑MUST BE SINGLE | Requires an acidic environment, such as dilute acetic acid; neutralizing pH can cause rapid aggregation. |
| 17 | Semaglutide | 7.0 – 7.8Near neutral | 🛑MUST BE SINGLE | Long-acting GLP-1 with proprietary preservatives; mixing alters solubility and release kinetics. |
| 18 | Tirzepatide | 6.5 – 7.5Near neutral | 🛑MUST BE SINGLE | Dual agonist formulated for extended seven-day stability; altering the solution environment risks precipitation. |
| 19 | Retatrutide | 6.5 – 7.5Near neutral | 🛑MUST BE SINGLE | Triple agonist engineered for precise depot release; best kept in a dedicated single-compound vial. |
| 20 | CJC-1295 (w/ DAC) | 6.0 – 7.0Near neutral | 🛑MUST BE SINGLE | The Drug Affinity Complex covalently binds albumin; co-mixing may disrupt the binding mechanism. |
| 21 | Tesamorelin | 5.0 – 6.5Mildly acidic | 🛑MUST BE SINGLE | Delicately folded 44-amino-acid structure; prone to enzymatic and mechanical degradation if mixed. |